Construction of enantiomerically enriched diazo compounds using diazo esters as nucleophiles: Chiral Lewis base catalysis

H Mao, A Lin, Y Shi, Z Mao, X Zhu, W Li…

Index: Mao, Haibin; Lin, Aijun; Shi, Yan; Mao, Zhijie; Zhu, Xuebin; Li, Weipeng; Hu, Hongwen; Cheng, Yixiang; Zhu, Chengjian Angewandte Chemie - International Edition, 2013 , vol. 52, # 24 p. 6288 - 6292 Angew. Chem., 2013 , vol. 125, # 24 p. 6408 - 6412,5

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Citation Number: 21

Abstract

Diazo compounds are remarkably versatile metal carbene precursors which participate in metal-catalyzed rearrangements, cycloadditions, XÀH (X= C, N, O, Si, S, etc.) bond insertions, and ylide-forming reactions with concomitant expulsion of N2.[1] These compounds also take part in 1, 3-dipolar cycloaddition reactions of a wide range of dipolarophiles with retention of the CN2 moiety.[2] Because of their unique properties and ...