Abstract: Variable-temperature 'H NMR and IR studies of triamide 1 and related compounds indicate that 1 undergoes dramatic temperature-dependent conformational changes in relatively nonpolar solvents (methylene chloride and chloroform). The folding pattern favored at low temperatures in thesechlorocarbons (IC) contains a single C= O-. HN hydrogen bond in a nine-membered ring, while a folding pattern containing only a six- ...
