Synthesis of (N, N'-bis (5-benzoyl-4-phenylthiazol-2-yl)-N, N'-bisbenzyl) ethane-1, 2-diamines

S Asha, SL Manju, NS Pradeep, V George…

Index: Asha; Manju; Pradeep; George; Rajasekharan Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2008 , vol. 47, # 11 p. 1726 - 1730

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Abstract

Abstract: Synthesis of [N, N′-bis (N-benzoylthiocarbamoyl)-N, N′-bis (benzyl)] ethane-1, 2- diamines 4a-h, their cyclization to [N, N′-bis (5-benzoyl-4-phenylthiazol-2-yl)-N, N′-- bisbenzyl] ethane-1, 2-diamines 5a-h by reaction with phenacyl bromide and the results of antibacterial activity assay of 4a-h and 5a-h are reported.