Tetrahedron letters

Efficient construction of polycyclic alkaloid synthetic precursors by a xanthate free radical addition and Mannich cyclisation cascade

EW Tate, SZ Zard

Index: Tate, Edward W.; Zard, Samir Z. Tetrahedron Letters, 2002 , vol. 43, # 26 p. 4683 - 4686

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Citation Number: 20

Abstract

Routes to synthetic precursors of Lupin and Eburna alkaloids have been developed, featuring the rapid construction of highly functionalised intermediates by the intermolecular radical coupling of xanthates and alkenes, followed by acid-mediated condensation– cyclisation.