Journal of the American Chemical Society

The Synthesis of δ-(p-Chlorophenyl)-hydantoic Acid-Cl36

HH Woeber

Index: Woeber Journal of the American Chemical Society, 1952 , vol. 74, p. 1354

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Citation Number: 4

Abstract

In a study of the biological effect of analogs of the naturally occurring amino acids, D, La- aminocyclopropylacetic acid was synthesized. It was prepared by a Strecker synthesis from cyclopropanecarboxaldehyde. The intermediate hydroxynitrile was aminated in methanolic ammonia. Because of the instability of cyclopropane compounds toward acids the hydrolysis was carried out with barium hydroxide. 2 Like many other D, L-amino acids ...