Convenient new procedures for the synthesis of ethoxythiocarbonyl derivatives of amino acids

G Barany, BW Fulpius, TP King

Index: Barany,G. et al. Journal of Organic Chemistry, 1978 , vol. 43, p. 2930 - 2932

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Citation Number: 19

Abstract

1 developed for peptide synthesis (2 in Scheme I). They are also intermediates in the preparation of N-thiocarboxy anhydrides 3 of a-amino acids (1, 3-thiazolidine-2, 5- dione~),~~,~) which were reported to have certain advantages for peptide synthe~ is~,~ by comparison to their oxygen analogues, N-carboxy anhydrides. Etc derivatives la and IC have also been explored for use as reversible amino protecting groups6 and in a scheme ...