Dotzauer et al. synthesized 2, 4-diamino-9H-pyrimido [4, 5-b] indol-6-ole (1) and N- substituted derivatives as a prototype of a series of ellipticine analogues by an extension of the Nenitzescu reaction using 1, 4-benzoquinone (4) and pyrimidine-2, 4, 6-triamines. These indole derivatives showed interesting antitumor activity [1-3]. Related to these compounds, we planned pyridine-2, 4, 6-triamine (5) to react as a new type of enamine component with ...
