N1-SUBSTITUTED TETRA-BENZAMIDINES-INHIBITION OF DNA-PROTEIN INTERACTIONS AND INVITRO TUMOR-CELL GROWTH

…, C Nastruzzi, C Mischiati, R Gambari

Index: Ferroni; Simoni; Binato; Nastruzzi; Manfredini; Orlandini; Feriotto; Gambari Farmaco, 1991 , vol. 46, # 11 p. 1311 - 1321

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Citation Number: 3

Abstract

The pharmacological-mediated inhibition of the interaction between regulatory proteins and target DNA sequences could represent a potential experimental strategy to control growth of neoplastic cells, viral DNA replication and biological life cycle of infectious microorganisms.