Molecular recognition of nucleotides by the guanidinium unit at the surface of aqueous micelles and bilayers. A comparison of microscopic and macroscopic interfaces

M Onda, K Yoshihara, H Koyano, K Ariga…

Index: Onda; Yoshihara; Koyano; Ariga; Kunitake Journal of the American Chemical Society, 1996 , vol. 118, # 36 p. 8524 - 8530

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Citation Number: 171

Abstract

Molecular recognition of the guanidinium/phosphate pair was investigated at microscopic interfaces of aqueous micelles and bilayers. Monoalkyl and dialkyl amphiphiles with guanidinium head groups were synthesized and dispersed in water to form micelles and bilayers having guanidinium groups at the aggregate surface. Binding of nucleotides such as AMP to these functionalized aggregates was evaluated by using an equilibrium dialysis ...