Unlike alkyl bromides and iodides, alkyl chlorides are shown to be stable to direct fluorination, even under ultraviolet irradiation, at temperatures of 30 OC and below. Although less reactive than the bromides and iodides, F-alkyl chlorides may be derivatized, presenting another example of direct fluorination-survivable functionality. High (63%) to moderate (32%) isolated yields of the analogous perfluoroalkyl chlorides can be ...
