Synthesis of diarlpropynones and their antibiotic activity

LD Gavrilov, VI Meshcheryakov, NP Glazunova…

Index: Gavrilov,L.D. et al. Pharmaceutical Chemistry Journal, 1978 , vol. 12, # 9 p. 1146 - 1149 Khimiko-Farmatsevticheskii Zhurnal, 1978 , vol. 12, # 9 p. 42 - 45

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Abstract

In an earlier con~ nunication [i] we reported the results of a study of the antimicrobial action of some acetylenic ketoesters which were shown to be highly active against dermatophytes, but had very little effect on gram-positive and gram-negative bacteria. In the present work,