Abstract A pair of pramoxine-based compounds, K-94 and K-95, which are potential local anesthetic and anticholinergic agents, were synthesized using a previously synthesized Schiff base of 2-diethylamine chloride and potassium carbonate. Of the compounds synthesized, compound K-94 was new. Moreover, RM, a physicochemical parameter, has been calculated for both compounds in order to investigate the effect of these structural ...