Bioorganic & medicinal chemistry

Novel antitumor agent family of 1H-benzo [c, d] indol-2-one with flexible basic side chains: synthesis and biological evaluation

H Yin, Y Xu, X Qian

Index: Yin, Hong; Xu, Yufang; Qian, Xuhong Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 3 p. 1356 - 1362

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Citation Number: 27

Abstract

A series of mono-1H-benzo [c, d] indol-2-one with different amine side chains and bis-1H- benzo [c, d] indol-2-one as novel family of DNA intercalators were designed and synthesized, the contributions of aromatic chromophores and amine side chains for DNA ...