A modular approach to α, β-unsaturated N-aryl ketonitrones has been developed. Specifically, condensation of anilines and enals followed by alkylation of the resulting α, β- unsaturated imines provided N-allyl anilines, which were subjected to oxidation with Oxone® to form α, β-unsaturated N-aryl ketonitrones. This modular approach is general and provides rapid access to diversely substituted α, β-unsaturated N-aryl ketonitrones with a ...
