The stereochemistry of the intramolecular, 1, 3-dipolar cycloaddition of several methyl- substituted N-methyl-C-6-heptenylnitrones was studied. The major product isoxazolidines were confirmed to have the 7-aza-8-oxabicyclo [4.3. 0] nonane (3a, 4, 5, 6, 7, 7a-hexahydro- 2, 1-benzisoxazoline, hydrindan) skeleton. The stereochemistry at the ring fusion was assigned primarily on the basis of nmr spectral evidence. It was found that cyclization of ...
[Jiricny, Josef; Orere, Daniel M.; Reese, Colin B. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 1487 - 1492]
