Tetrahydroisoquinolines as subtype selective estrogen agonists/antagonists

…, BA Lefker, KO Cameron, RF Day, FM Mangano…

Index: Chesworth, Richard; Zawistoski, Michael P.; Lefker, Bruce A.; Cameron, Kimberly O.; Day, Robert F.; Mangano, F. Michael; Rosati, Robert L.; Colella, Stacy; Petersen, Donna N.; Brault, Amy; Lu, Bihong; Pan, Lydia C.; Perry, Pia; Ng, Oicheng; Castleberry, Tessa A.; Owen, Thomas A.; Brown, Thomas A.; Thompson, David D.; DaSilva-Jardine, Paul Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 11 p. 2729 - 2733

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Citation Number: 34

Abstract

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Two series of 6-hydroxy and 7-hydroxy tetrahydroisoquinolines were prepared. Evaluating a range of C-1, C-4, and N-substituents led to the discovery of ER α and ER β selective analogs. ... Two series of 6-hydroxy and 7-hydroxy tetrahydroisoquinolines were prepared. Evaluating a ...