Organocatalytic Enantioselective α-Hydroxymethylation of Aldehydes: Mechanistic Aspects and Optimization

RK Boeckman Jr, KF Biegasiewicz…

Index: Sui, Bin; Yeh, Edmund A.-H.; Curran, Dennis P. Journal of Organic Chemistry, 2010 , vol. 75, # 9 p. 2942 - 2954

Full Text: HTML

Citation Number: 8

Abstract

... The Journal of Organic ... J. Org. ... Over the course of the past decade, synthetic organic chemists have begun to address the aforementioned limitations of auxiliary based methods through applications of catalysis, including organocatalysis.(7-11) These methods have become ...

~97%

~98%

Synthesis of (R)-and (S)-10, 16-dihydroxyhexadecanoic acid: ...

[Ahmed, Aqeel; Crawford, Terry; Gould, Stephanie; Ha; Hollrah, Monica; Noor-E-Ain, Farhana; Dickman, Martin B.; Dussault, Patrick H. Phytochemistry, 2003 , vol. 63, # 1 p. 47 - 52]

Facile and stereoselective synthesis of (Z)-15-octadecenoic ...

[Rawling, Tristan; Duke, Colin C.; Cui, Pei H.; Murray, Michael Lipids, 2010 , vol. 45, # 2 p. 159 - 165]

Studies in lipid mimics. Synthesis and carbon-13 relaxation ...

[Waugh, Kristy M.; Berlin, K. Darrell Journal of Organic Chemistry, 1984 , vol. 49, # 5 p. 873 - 878]