Accounts of Chemical Research

Synthesis of polycyclics via aryne arylation reactions

ER Biehl, SP Khanapure

Index: Khanapure, Subhash P.; Biehl, Edward R. Heterocycles, 1988 , vol. 27, # 11 p. 2643 - 2650

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Citation Number: 52

Abstract

The benzyne molecule was proposed and supported by Wittig'as early as 1942 to explain the remarkable ease with which nonactivated haloarenes undero nucleophilic substitution in the presence of a strong base. The intermediacy of benzynes in such reactions was shown