New pyridino-18-crown-6 ligands containing two methyl, two tert-butyl, or two allyl substituents on chiral positions next to the pyridine ring

Y Habata, JS Bradshaw, JJ Young…

Index: Jones, Brian A.; Bradshaw, Jerald S.; Brown, Phillip R.; Davidson, Richard B.; Christensen, James J.; Izatt, Reed M. Heterocycles, 1984 , vol. 21, # 2 p. 386

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Citation Number: 41

Abstract

Chiral 2, 16-diallyl-, 2, 16-dimethyl-, and 2, 16-di-tert-butylpyridino-18-crown-6 ligands have been prepared by treating the appropriate chiral α, α'-disubstituted pyridinedimethanol with tetraethylene glycol ditosylate in the presence of base. In these reactions, chiral 2: 2 dimers