SYNTHESIS OF BENZO [1, 2-b: 5, 4-b′]-DIFURANYL-TRIAZOLES,-OXADIAZOLES,-THIAZOLIDINONES,-THIADIAZOLES, AND THE USE OF DNA IN EVALUATION …

…, MM Girges, AH Abdel-Rahman, FA Badria

Index: Keshk; Abu-Hashem; Girges; Abdel-Rahman; Badria Phosphorus, Sulfur and Silicon and the Related Elements, 2004 , vol. 179, # 8 p. 1577 - 1593

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Citation Number: 8

Abstract

Benzo [1, 2-b: 5, 4-b′] difuran-2-carbohydrazides 5a, b were reacted with aryl or alkyl isothiocyanates to give the corresponding thiosemicarbazides 6a–h. Cyclization of the substituted thiosemicarbazides with sodium hydroxide led to the formation of benzo [1, 2-b: 5, 4-b′] difuranyl-1, 3, 4-triazoles 7a–f. Desulfurization of thiosemicarbazides by mercuric oxide gave benzo [1, 2-b: 5, 4-b′] difuranyl-1, 3, 4-oxadiazoles 8a–f. Treatment of ...