Decreased catecholamine sensitivity and β-adrenergic-receptor density in failing human hearts

MR Bristow, R Ginsburg, W Minobe…

Index: Gerhard; Schunack Archiv der Pharmazie, 1980 , vol. 313, # 9 p. 780 - 784

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Citation Number: 2397

Abstract

... binding experiments by incubating 300 μl of the membrane preparation with six to eight increasing concentrations of [ 3 H]DHA (1.1 to 11.0 nM in most cases) in the presence or absence of 10 –3 M L-isoproterenol, in a total volume of 450 ... 1980; 26:2245–9. CrossRef | Web ...