Journal of Chemistry

Synthesis and Antifungal Activity of 2-Ketophenyl-3-substituted aryl-1-thiazolidin-4-ones

V Vats, RK Upadhyay, P Sharma

Index: Vats, Vishnu; Upadhyay; Sharma, Prathibha E-Journal of Chemistry, 2010 , vol. 7, # 3 p. 1040 - 1044

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Citation Number: 3

Abstract

A new series of 2-ketophenyl-3-substituted aryl-1-thiazolidin-4-ones were synthesized by cyclocondensation of ketoazomethines and thioglycolic acid. Ketoazomethines were synthesized by condensation of phenyl glyoxal (prepared by partial oxidation of acetophenone) and various para-substituted anilines. Their structures were elucidated by elemental analysis, IR and H1 NMR; they were screened for their antifungal activity ...