Abstract Syntheses for 9-(β-D-ribofuranosyl) uric acid (16) and its 5′-monophosphate 14 have been achieved starting from guanosine and applying the 2-(p-nitrophenyl) ethyl group for protection of the aglycon moiety as well as the phosphate function. A more efficient and direct approach to 14 uses O 6, O 8-dibenzyl protection and phosphorylation by the Yoshikawa procedure. The various protected intermediates have been characterized by ...
