Bulletin of the Chemical Society of Japan

The reaction of 2-substituted cycloalkanones with aldehydes under acidic conditions

T Sato, K Hayase

Index: Sato, Tadashi; Hayase, Kengo Bulletin of the Chemical Society of Japan, 1991 , vol. 64, # 11 p. 3384 - 3389

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Citation Number: 4

Abstract

3386 Tadashi Sato and Kengo Hayase [Vol. 64, No. 11 are obtained under acidic conditions.8' It has been well documented that the aldol reaction is reversible and accompanied by a facile dehydration in protic solvents. Thus the thermodynamically most stable compounds might be the product under these conditions. On the other hand, the kinetic aldols can be isolated without being dehydrated, by starting from the corresponding derivatives of the substrates ...