e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Journal of Organometallic Chemistry
Synthesis of 2-decenedioic acid (royal jelly acid) by sequential carbonylation of butadiene catalyzed by a palladium—phosphine complex and dicobalt octacarbonyl
J Tsuji, H Yasuda
Index: Tsuji,J.; Yasuda,H. Journal of Organometallic Chemistry, 1977 , vol. 131, p. 133 - 135
Abstract Carbonylation of butadiene in t-butyl alcohol catalyzed by a palladium complex gave t-butyl-3, 8-nonadienoate (I). Further carbonylation of I in methanol with Co 2 (CO) 8 afforded t-butylmethyl-3-decenedioate (II) as the main product. Hydrolysis and base- catalyzed isomerization of II produced E-2-decenedioic acid.
