Bioconjugate chemistry

Phenylthiocarbamate or N-carbothiophenyl group chemistry in peptide synthesis and bioconjugation

O Melnyk, N Ollivier, S Besret, P Melnyk

Index: Pira, Silvain L.; Boll, Emmanuelle; Melnyk, Oleg Organic Letters, 2013 , vol. 15, # 20 p. 5346 - 5349

Full Text: HTML

Citation Number: 3

Abstract

The design of novel chemoselective and site-specific ligation methods provides new tools for obtaining complex scaffolds, peptidomimetics, and peptide conjugates. The chemistry of the N-phenylthiocarbonyl group has led to several developments in peptide ligation