Abstract A new short and highly efficient synthesis of (5)??2, 3??dimethoxy??N [(1??ethyl??2?? pyrrolidinyl) methyl]??5??iodobenzamide (epidepride, 1) from 3??methoxy??salicylaldehyde (o?? vanillin, 2) and 3??methoxysalicyclic acid (6) was achieved by employing a new iodination method with iodine monochloride and iodine nitrate under basic conditions.
