Abstract A novel and recyclable catalyst, a C 3-symmetrical cinchonine-squaramide, has been developed for the asymmetric Michael addition of 1, 3-dicarbonyl compounds to nitroalkenes. When using only 1 mol% of catalyst 1a for the reaction, high reaction yields with excellent enantioselectivities and diastereoselectivities (up to 96% yield,> 99% ee,> 99: 1 dr) were achieved, in which the results for cyclic keto esters are the best ever achieved. ...
![3-[(1R)-2-nitro-1-phenylethyl]pentane-2,4-dione Structure](https://image.chemsrc.com/caspic/355/189952-21-4.png)