Polycyclic N??heterocyclic compounds. 51. Synthesis of novel 12??substituted 11, 13, 15??triazasteroidal compounds and their inhibitory activity on platelet aggregation

…, T Arichi, H Ohtomo, T Nakayama…

Index: Sasaki, Kenji; Arichi, Takeshi; Ohtomo, Hiromi; Nakayama, Taiji; Hirota, Takashi Journal of Heterocyclic Chemistry, 1996 , vol. 33, # 6 p. 1663 - 1669

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Citation Number: 12

Abstract

Abstract Synthesis of 11-substituted 1, 2, 4, 5-tetrahydrobenzo [h] imidazo [1, 2-c] quinazolines corresponding to 12-substituted 11, 13, 15-triazasteroid is described. Evaluation on inhibitory activity against collagen-induced platelet aggregation of these compounds and their precursors was also investigated.