Il Farmaco

Cytotoxic–antineoplastic activity of acetyl derivatives of prenylnaphthohydroquinone

…, C Araya, MD García-Grávalos, A San Feliciano

Index: Molinari, Aurora; Oliva, Alfonso; Del Corral, Jose Ma. Miguel; Castro, Ma. Angeles; Araya, Claudia; Garcia-Gravalos, Ma. Dolores; San Feliciano, Arturo Farmaco, 2004 , vol. 59, # 8 p. 651 - 656

Full Text: HTML

Citation Number: 10

Abstract

Several acetyl derivatives of prenylnaphthohydroquinone have been synthetised and evaluated for their cytotoxicity against A-549 human lung carcinoma and H-116 human colon carcinoma neoplastic cells. The IC50 values against A-549 are compared with those observed for previously reported unsubstituted derivatives.