Tetrahedron

Alkylation of heteroaryl alkyl metals by bistrialkylsilylperoxides

E Epifani, S Florio, L Troisi

Index: Epifani, Erbana; Florio, Saverio; Troisi, Luigino Tetrahedron, 1990 , vol. 46, p. 4031 - 4038

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Citation Number: 20

Abstract

Heteroaryl alkyl metals 3 undergo methylation and ethylation upon treatment with bistrimethylsilylperoxide la and bistriethylsilylperoxide 1b. Benzothiazolylderivatives 3c-d and 3h-j react with la giving trimethylsilyloxylation other than methylation products. The reaction of 3a-b with la leads also to the trimethylsilylation product 1. The reaction of 3g, 3c and 3k with 1b provides the ethylated derivatives 2h, 2d and 2n respectively. No reaction ...