Biocatalytic separation of α-hydroxyphosphonates with lipase of Burkholderia cepacia

OO Kolodyazhnaya, OI Kolodyazhnyi

Index: Kolodyazhnaya; Kolodyazhnyi Russian Journal of General Chemistry, 2010 , vol. 80, # 8 p. 1718 - 1719

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Citation Number: 5

Abstract

In recent years enzymes are with increasing frequency used to obtain the enantiomerically pure organophosphorus compounds [1–4]. In this work we found that lipase of Burkholderia cepacia (BCL) immobilized on diatomite [5, 6] is effective biocatalyst, which makes possible a kinetic separation of racemic α-hydroxyphosphonates into enatiomers. In the presence of this lipase vinyl acetate esterifies only (S)-enantiomer of racemic α-hydroxyphosphonates ...