Enantioselective catalysts based on the chiral fragment (η 5-C 5 Me 5) Ir (Prophos) for Diels–Alder reactions

…, F Viguri, A Asenjo, FJ Lahoz, P García-Orduña…

Index: Carmona, Daniel; Viguri, Fernando; Asenjo, Ainara; Lahoz, Fernando J.; Garcia-Orduna, Pilar; Oro, Luis A. Organometallics, 2012 , vol. 31, # 12 p. 4551 - 4557

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Citation Number: 3

Abstract

Abstract The aqua complex (S Ir, RC)–[(η 5-C 5 Me 5) Ir (Prophos)(H 2 O)][SbF 6] 2 [Prophos=(R)-propane-1, 2-diyl-bis (diphenylphosphane)] is an active precursor for the asymmetric Diels–Alder reaction of acyclic enals with cyclopentadiene, 2, 3- dimethylbutadiene and isoprene. Enantioselectivities up to 78% ee are achieved. The intermediate Lewis acid-dienophile complex (S Ir, RC)–[(η 5-C 5 Me 5) Ir (Prophos)(ethyl ...