Abstract Diels-Alder heterocycloaddition reactions of 2, 5, 8-quinolinetriones and 1- azadienes afford 1, 8-diaza-2, 9, 10-anthracenetri-ones, which are simple analogues of the antitumoral antibiotic diazaqui-nomicin A. Cytotoxicity in this series and antitumor activity of the lead compound, 6-methyl-1, 8-diaza-2, 9, 10-anthracenetrione, are reported.
![2-methoxy-7-methylpyrido[3,2-g]quinoline-5,10-dione Structure](https://image.chemsrc.com/caspic/258/143726-26-5.png)