Crude Drugs Effective on Visceral Larva Migrans. Part XVIII. Synthesis and Nematocidal Activity of Aralkyl-and Aralkenylamides Related to Piperamide on Second- …

…, N TAKIMOTO, N AKAO, K KONDO, Y TSUDA

Index: Kiuchi; Nishizawa; Kawanishi; Kinoshita; Ohsima; Uchitani; Sekino; Ishida; Kondo; Tsuda Chemical and Pharmaceutical Bulletin, 1992 , vol. 40, # 12 p. 3234 - 3244

Full Text: HTML

Citation Number: 0

Abstract

Seventy-nine aralkyl-and aralkenylamides related to piperamides were synthesized and their nematocidal activity against second-stage larvae of dog roundworm, Toxocara canis, was examined. The activity was greatly dependent on the alkyl chain length and the nature

 Related Synthetic Route

~37%

~%

~%

~60%

~%

~%

~%

~%

~%

~28%

~%

~%

~%

~%

~60%

~%

~%

~%

~%

~74%

~%

~%

~%

~%

~%

~%