Synthesis of aryl aldimines and their activity against fungi of clinical interest

…, LP Rodrigues, AA Sabino, RB Alves…

Index: da Silva, Cleiton M.; da Silva, Danielle L.; Martins, Cleide V.B.; de Resende, Maria A.; Dias, Esther S.; Magalhaes, Thais F.F.; Rodrigues, Leticia P.; Sabino, Adao A.; Alves, Rosemeire B.; de Fatima, Angelo Chemical Biology and Drug Design, 2011 , vol. 78, # 5 p. 810 - 815

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Citation Number: 13

Abstract

Aldimines are aldehyde-derived compounds that contain a C= N group. Besides its broad industrial applications, this class of non-naturally occurring compounds are found to possess antibacterial, antifungal, antimalarial, antiproliferative, antiinflammatory, antiviral, and antipyretic properties. Based on this, six aryl aldimines were synthesized from the condensation of aromatic amines with benzaldehydes. The antifungal activities of ...