Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Four-step synthesis of achiral and chiral 4-(1-pyrrolidinyl)-2(5H)-thiophenones with 61 and 66% overall yields are described. The γ-alkylation reaction studies and synthetic applications toward the thiolactomycin analog are also reported. ... Methyl acetoacetate 4 in benzene was ...
