Abstract The synthesis of 3-{substituted 1, 3-thiazol-5-yl}-1-substituted 1 H-pyrazole-4- carboxylates (4a–n) has been achieved in facile manner by the reaction between 2- aminothiazoles, dimethylformamide dimethyl acetal and hydrazine. All the synthesized compounds were characterized by spectral and elemental analyses. These compounds were also evaluated against anti-inflammatory activity and showing promising activities.
![1-[2-(N-methylanilino)-4-phenyl-1,3-thiazol-5-yl]ethanone Structure](https://image.chemsrc.com/caspic/031/111753-03-8.png)