Radical Synthesis of Guanidines from N??Acyl Cyanamides

MH Larraufie, C Ollivier, L Fensterbank…

Index: Larraufie, Marie-Helene; Ollivier, Cyril; Fensterbank, Louis; Malacria, Max; Lacote, Emmanuel Angewandte Chemie - International Edition, 2010 , vol. 49, # 12 p. 2178 - 2181

Full Text: HTML

Citation Number: 48

Abstract

Guanidines—especially those embedded into polyclic frameworks—are an important structural unit of valuable synthetic intermediates and/or natural products.[1] Therefore guanidines are appealing targets for total synthesis,[2] bio-inspired molecular recognition,[3] organocatalysis,[4] and coordination chemistry.[5] The development of innovative, efficient, and flexible methods to access these compounds thus remains an important goal.[6]