Diagnostic and therapeutic potential of poly (benzyl L??glutamate)

DJ Yang, C Li, S Nikiforow, MB Gretzer…

Index: Yang, David J.; Li, Chun; Nikiforow, Sarah; Gretzer, Matthew B.; Kuang, Li-Ren; et al. Journal of Pharmaceutical Sciences, 1994 , vol. 83, # 3 p. 328 - 331

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Citation Number: 11

Abstract

Abstract Poly (benzyl L-glutamate)(PBLG) microcapsules, prepared by a solvent evaporation technique for intravenous injection, are evaluated for their potential use in diagnostic computed tomographic enhancement of liver images. The smaller microcapsules,< 3 μm, loaded with a radiopaque contrast material, ethyl iopanoate (IOPAE), produced prolonged opacification of the liver when delivered intravenously. In vivo tissue distribution studies of ...