Journal of Heterocyclic Chemistry

Chemistry of thienopyridines. XXIX. The reissert??henze reaction as a route to simple c??substituents alpha to the heteronitrogen atom

LH Klemm, DR Muchiri

Index: Klemm, L. H.; Muchiri, Daniel R. Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 213 - 217

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Citation Number: 13

Abstract

Abstract Treatment of a thienopyridine N-oxide with benzoyl chloride and cyanide ion (Reissert-Henze reaction) was shown to produce the corresponding cyanothienopyridine (43-84% yield in three parent systems), wherein the cyano substituent occurs alpha to the