e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Pharmaceutical Chemistry Journal
… electrophilic reactions. VII. The synthesis and properties of the stereoisomers of 2-substituted 5-hydroxymethyl-5-(2, 4-disubstituted 1, 3, 5-triazin-6-yl) amino-1, 3- …
BO Kraiz, AL Remizov
Index: Kraiz, B. O.; Remizov, A. L. Pharmaceutical Chemistry Journal, 1981 , vol. 15, # 1 p. 23 - 28 Khimiko-Farmatsevticheskii Zhurnal, 1981 , vol. 15, # 1 p. 45 - 50
In all the isomers, the substituent at C 2 of the dioxane ring occupies an equatorial position, since if it were in the axial position, there would be a strong 1, 3-interaction with the axial protons at C 4 and C a of the 1, 3~ dioxane ring; in additionj the signal of the equatorial
![(5-{[4,6-Bis(1-aziridinyl)-1,3,5-triazin-2-yl]amino}-2-phenyl-1,3 -dioxan-5-yl)methanol Structure](https://image.chemsrc.com/caspic/463/73322-82-4.png)
![[5-[[4,6-bis(aziridin-1-yl)-1,3,5-triazin-2-yl]amino]-2-propan-2-yl-1,3-dioxan-5-yl]methanol Structure](https://image.chemsrc.com/caspic/080/67026-17-9.png)
![[5-[[4,6-bis(aziridin-1-yl)-1,3,5-triazin-2-yl]amino]-2-(furan-2-yl)-1,3-dioxan-5-yl]methanol Structure](https://image.chemsrc.com/caspic/032/67026-18-0.png)
