Four homoisoflavanones of the 3-benzylidene-4-chromanone type, some of which were previously isolated from Caesalpinia pulcherrima, were synthesised to determine their anti- inflammatory activity and cytotoxicity. A range of four different homoisoflavanones (compounds 4a–4d) were synthesised from the corresponding substituted phenols. 1H-and 13C-NMR data together with high-resolution mass spectroscopy data were employed to ...