Tetrahedron

Design and synthesis of mannose analogues as inhibitors of α-mannosidase

SK Maity, SK Dutta, AK Banerjee, B Achari, M Singh

Index: Maity, Sanat K.; Dutta, Samir K.; Banerjee, Asish K.; Achari, Basudeb; Singh, Manoranjan Tetrahedron, 1994 , vol. 50, # 23 p. 6965 - 6974

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Citation Number: 26

Abstract

A series of N-, C-and S-mannopyranosyl derivatives (4, 9-16) have been synthesised and their inhibitory activity tested towards jackbean α-mannosidase (EC 3.2. 1.24). These compounds are of mechanistic and synthetic interest in the design of new α-mannosidase inhibitors.