Tetrahedron Letters

Dodecylphosphonic acid (DPA): a highly efficient catalyst for the synthesis of 2H-indazolo [2, 1-b] phthalazine-triones under solvent-free conditions

M Kidwai, A Jahan, R Chauhan, NK Mishra

Index: Kidwai, Mazaahir; Jahan, Anwar; Chauhan, Ritika; Mishra, Neeraj Kumar Tetrahedron Letters, 2012 , vol. 53, # 14 p. 1728 - 1731

Full Text: HTML

Citation Number: 37

Abstract

A new green protocol has been developed for the synthesis of 2H-indazolo [2, 1-b] phthalazine-triones via one-pot, three-component condensation reaction of aromatic aldehydes with 1, 3-dicarbonyl compounds and phthalhydrazide using reusable dodecylphosphonic acid (DPA) as heterogeneous solid acid catalyst under solvent-free conditions. This protocol provides a novel and improved method for obtaining 2H-indazolo ...