Organic letters

Copper-catalyzed iminoiodane-mediated aminolactonization of olefins: Application to the synthesis of 5, 5-disubstituted butyrolactones

D Karila, L Leman, RH Dodd

Index: Benohoud, Meryem; Leman, Loic; Cardoso, Silvia H.; Retailleau, Pascal; Dauban, Philippe; Thierry, Josiane; Dodd, Robert H. Journal of Organic Chemistry, 2009 , vol. 74, # 15 p. 5331 - 5336

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Citation Number: 14

Abstract

A copper (I)-catalyzed reaction of a variety of 4-aryl-pent-4-enoates with nosyliminoiodane generated in situ provides the corresponding 5-aryl-5-nosylamidomethylbutyrolactones. The reaction presumably proceeds via an aziridine intermediate, which could be isolated in one