Electrostatic control of regioselectivity in competing bimolecular eliminations

EJ Grubbs, SP Schmidt, CT Wang, Z Chen…

Index: Grubbs, Edward J.; Schmidt, Stephen P.; Wang, Charles T.; Chen, Zhangping; Hamed, Ashraf A.; et al. Journal of Organic Chemistry, 1985 , vol. 50, # 16 p. 2886 - 2892

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Citation Number: 2

Abstract

The iabmeric trans-11, 12-dichloro-9, lO-dihydro-9, lO-ethano-l-anthroic acids (1 and 2) have been prepared and characterized. Base-induced dehydrochlorinations of these and the corresponding cis-dichloroethano derivatives 3 and 4 were conducted under several sets of base/solvent conditions. Preparations and dehydrochlorinations of 24 trans-ll, l2- dichloro-9, 10-dihydro-9, 10-ethano-9-anthryl] ethanoic acid (15) and the corresponding ...