Total Synthesis of Clathculins A and B

…, GL Anderson, SG Brown, EE Schultz

Index: Hoye, Rebecca C.; Anderson, Gretchen L.; Brown, Susan G.; Schultz, Erica E. Journal of Organic Chemistry, 2010 , vol. 75, # 21 p. 7400 - 7403

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Citation Number: 11

Abstract

Clathculins A and B represent a new class of vic-diamine alkaloids containing a PA2 unit as the basic structure. We report the first total syntheses of 1 and 2, which confirm the assigned structure of each. Dependence of their NMR spectroscopic behavior as a function of protonation state has been observed.