Abstract: A series of 1-cyclopropyl-6-fluoro-1, 4-dihydro-4-oxo-7-[chloro/1-piperazinyl/4- methyl-1-piperazinyl/4-ethyl-1-piperazinyl/4-hydroxyethyl-1-piperazinyl/imidazolyl/ morpholinyl]-3 [N-(substituted phenyl amino) carbonyl] quinoline 5-11a-j have been prepared by using substituted arylamine at C-3 position and 1-piperazine/4-methyl-1- piperazine/4-ethyl-1-piperazine/4-hydroxyethyl-1-piperazine/imidazole/morpholine at C-7 ...