Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... The conversion of readily available 2-halobenzaldehydes into indolo[2,1-a]isoquinolines in two operations represents a very direct entry to this class of molecules. ... Indolo[2,1-a]isoquinolines and their dihydro analogs exhibit a diverse array of activities. These compounds are components in tubulin-binding ...